The handling characteristics of i-FACTOR™ Putty allow it to be used in contained implants such as spinal interbody fusion devices. This novel mechanism of action enhances the body's natural bone healing process resulting in safe, predictable bone formation. An isotonic solution is a solution that has the same tone as the biologic fluid.
I-FACTOR™ Putty combines a unique anorganic bone mineral (ABM) and small peptide (P-15™) that acts as an attachment factor for specific integrins on osteogenic cells. a nonelectrolyte with a molecular weight of 92. I hear surgeons and academia at the podium of every single biologics presentation at society meetings say the same thing: 'We need to make Shared by Kathie Austin iFACTOR is a market. Two product forms (Putty and Flex) allow clinicians to choose the handling characteristics best suited to specific applications. I-FACTOR™ bone graft is easy to use in a wide range of orthopedic and spine procedures. I-FACTOR™ demonstrates efficacy equivalent to autograft. PMA approved as a bone graft substitute for dental indications, with study outcomes proving clinical superiority to both alloplasts and allografts (DBM). I-FACTOR™ has been used in more than 2,000 spine and trauma surgeries worldwide. Unlike growth factor products, i-FACTOR™ only stimulates bone growth in the presence of bone forming cells, decreasing the likelihood of ectopic bone formation. I-FACTOR™ targets specific integrins in osteogenic cells to stimulate the natural bone healing process. I-FACTOR™ Biologic Bone Graft enables surgeons to avoid the morbidity of harvesting autograft.